Urea, also known as carbamide, is an organic compound with the chemical formula CO(NH2)2. This amide has two –NH2 groups joined by a carbonyl (C=O) functional group.
The reference site for Carbamide
WHAT IS carbamide?
Intra-amniotic Urea® (carbamide) is given by injection into the uterus to cause an abortion.
It is to be administered only by or under the immediate care of your doctor. It is available in the Parenteral Injection (U.S.) dosage form.
Brand Name(s): Ureaphil, Urea (Intra-amniotic)
CAS nº: 57-13-6
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The sections below will provide you with more specific information and guidelines related to carbamide and its correct use. Please read them carefully.
Carbamide has been approved by the Food and Drug Administration (FDA). However, a prescription is required for this medicine.
Why is this medication prescribed?
Intra-amniotic Urea® (carbamide) is given by injection into the uterus to cause an abortion. This medicine is to be administered only by or under the immediate care of your doctor. It is available in the Parenteral Injection (U.S.) dosage form.
Mechanism: Urea® kills the fetus, and prostaglandin helps ensure its expulsion.
Other uses for this medicine
This medication has not been approved for any alternative uses other than those mentioned in the product information section.
Note: Other forms of Urea® (other than intra-amniotic Urea®) do have other therapeutic uses which have not been mentioned here. Please consult these with your family doctor or local pharmacist.
Dosage and using this medicine
During the abortion procedure, you should drink fluids to help prevent your body from losing too much water.
The dose of this medication will vary from patient to patient. For your particular dose you will need to follow your doctor’s orders. The dose will be given by your doctor in a health care setting, such as a hospital or clinic. The following information includes only the average doses of Urea®:
For injection dosage form (for causing abortion):
Adults and teenagers-Up to 250 milliliters (mL) injected through the abdomen into the uterus after the same amount of fluid is taken out of the bag around the fetus (amniotic sac). The injection may be repeated 48 hours after the first dose if needed.
Contractions will begin within 8 to 12 hours and may last 48 hours before the fetus, placenta and membranes are expelled.
What special precautions should I follow?
BEFORE TAKING CARBAMIDE:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will need to consider together. For carbamide, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to Urea®. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Although there is no specific information comparing use of Urea® in teenagers with use in other age groups, this medicine is not expected to cause different side effects or problems in teenagers than it does in adults.
Although certain medications should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or non-prescription (over-the-counter [OTC]) medicine.
Other medical problems
The presence of other medical problems may affect the use of Urea®. Make sure you tell your doctor if you have any other medical problems, especially if you suffer from diabetes mellitus (sugar diabetes), fibroid tumors of the uterus, kidney disease, liver disease, or sickle cell disease.
What should I do if I forget a dose?
This does not apply to this medication.
What side effects can this medication cause?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your health care professional immediately if either of the following side effects occurs during the time that the injection is being given:
Pain in lower abdomen
Check with your health care professional as soon as possible if any of the following side effects occur:
Irregular heartbeat, muscle cramps or pain
Numbness, tingling, pain, or weakness in hands or feet
Unusual tiredness or weakness
Weakness and heaviness of legs
Other side effects may occur that usually do not need medical attention.
However, check with your health care professional if any of the following side effects continue or are bothersome:
Nausea or vomiting
Less common or rare
After the procedure is completed, this procedure may still produce some side effects that need medical attention.
Check with your doctor if you notice any of the following side effects:
Chills or shivering
Foul-smelling vaginal discharge
Increase in bleeding of the uterus
Pain in lower abdomen
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your health care professional.
What storage conditions are needed for this medicine?
The dose will be given by your doctor in a health care setting, such as a hospital or clinic. Therefore, the storage is taken care of by the healthcare center.
In case of an emergency/overdose
In case of complications after the procedure, contact your doctor or call the local emergency services at 911.
The possible complications that can occur during or after using carbamide are:
Retention of pieces of the placenta
Reaction to anesthesia
PICTURES OF carbamide PILLS
Below you will find images and specific information on the principal types of carbamide that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.